Together with researchers from Shanghai, AST co-founder Zhong-Lin Lu co-published a paper in Refractive Surgery titled 'A novel quick contrast sensitivity function test in Chinese adults with myopia and its related parameters'

Together with researchers from Fudan University, AST co-founder Zhong-Lin Lu co-published a paper in IOVS titled 'Contrast Sensitivity Function: A More Sensitive Index for Assessing Protective Effects of the Cilioretinal Artery on Macular Function in High Myopia'.

Together with researchers from Wenzhou and Shanghai, AST co-founder Zhong-Lin Lu co-published a paper in Eye and Vision titled 'Reduced contrast sensitivity function correlated with superficial retinal capillary plexus impairment in early stage of dysthyroid optic neuropathy'

Together with researchers from Fudan University and Shanghai, AST co-founder Zhong-Lin Lu co-published a paper in Eye and Vision titled 'Tolerance to lens tilt and decentration of two multifocal intraocular lenses: using the quick contrast sensitivity function method'

Together with network of researchers AST co-founder Zhong-Lin Lu co-published a paper in Ophthalmology and Therapy titled 'The Characteristics of Quick Contrast Sensitivity Function in Keratoconus and Its Correlation with Corneal Topography'

Together with researchers from Guangzhou, Zheijang, Hong Kong, and Shanghai, AST co-founder Zhong-Lin Lu co-published a paper in Frontiers in Neuroscience titled 'Assessing the contrast sensitivity function in myopic parafovea: A quick contrast sensitivity functions study'

Harvard Medical School researchers with senior author John Miller published an article "Active Learning to Characterize the Full Contrast Sensitivity Function in Cataracts" in the journal "Clinical Ophthalmology". In a prospective observational study of eyes with visually significant cataract, one of their findings was that contrast threshold at 6 cycles per degree, typically not tested with traditional contrast sensitivity charts, was significantly reduced even in cataractous eyes with good visual acuity (>= 20/25). They conclude that "CSF testing may enhance cataract evaluation and surgical decision-making, particularly in patients with subjective visual complaints despite good VA."

Together with researchers from Wenzhou Medical University, the Cixi's People Hospital, and NYU Shanghai, we published a paper in Frontiers in Medicine on "Contrast Sensitivity Is Associated With Chorioretinal Thickness and Vascular Density of Eyes in Simple Early-Stage High Myopia".

Together with Yukai Zhao from New York University and Fang Hou from Wenzhou Medical University, we published a paper in Journal of Vision on "Hierarchical Bayesian modeling of contrast sensitivity functions in a within-subject design".

We are happy to be chosen to be among the 8 finalists of the bytes4diabetes award 2022. This award is sponsored by BERLIN-CHEMIE AG with the goal to support innovative digital solutions to improve patient care in diabetes. The final winner will be announced during the DiaTec meeting on January 27th, 2022.

Together with Yukai Zhao from New York University, we published a paper in translational vision science & technology on "Quantifying Uncertainty of the Estimated Visual Acuity Behavioral Function With Hierarchical Bayesian Modeling".

Together with researchers from Ohio State University and Shanghai, AST co-founders Luis Lesmes and Zhong-Lin Lu published a paper in Frontiers in Neuroscience on "Evaluating the Performance of qVFM in Mapping the Visual Field of Simulated Observers With Eye Diseases". The authors conclude that "The qVFM method can be used to characterize residual vision of simulated ophthalmic patients. The study sets the stage for further investigation with real patients and potential translation of the method into clinical practice."

Together with researchers from Guangzhou and Shanghai, AST co-founder Zhong-Lin Lu published a paper in Frontiers in Psychology on "Meridian-Specific and Post-Optical Deficits of Spatial Vision in Human Astigmatism: Evidences From Psycho-Physical and EEG Scalings".

Researchers from Mass Eye and Ear published a review paper in the Journal of Clinical Medicine on "Measuring the Contrast Sensitivity Function in Non-Neovascular and Neovascular Age-Related Macular Degeneration: The Quantitative Contrast Sensitivity Function Test" and conclude that "Using active learning principles, the qCSF can efficiently measure contrast sensitivity across multiple spatial frequencies with both high sensitivity in detecting subtle changes in visual function and robust test–retest reliability, emerging as a promising visual function endpoint in AMD both in clinical practice and future clinical trials."

Together with researchers from Guangzhou, Hong Kong, and Shanghai, AST co-founder Zhong-Lin Lu published a paper in translational vision science & technology on "Sensitivity and Stability of Functional Vision Tests in Detecting Subtle Changes Under Multiple Simulated Conditions". The paper concludes that "Compared with visual acuity and chart-based CS tests, the quick CSF method provided more reliable and sensitive measures to detect small visual changes."

Click "View link" for more information

Our paper "Binocular Summation and Suppression of Contrast Sensitivity in Strabismus, Fusion and Amblyopia" was included in the Frontiers in Human Neuroscience top-10 list of "well-received spontaneous articles from the past couple of years, which have been specially handpicked by our Chief Editor, Prof. Jae Kun Shim. [...] All research presented here displays strong advances, in theory, experiment, and methodology with applications to compelling problems."

Researchers from the Naval Medical Center in San Diego used the qCSF to assess vision in 58 active U.S. military service members who elected LASIK or PRK-MMC refractive surgery for myopia treatment. Results were published in Military Medicine, and the researchers conclude that "The standard black-on-white high-contrast, chart-based visual acuity test is weak in predicting quality of vision. The qCSF detects mild-to-moderate visual changes and is suitable for quality of vision assessment following refractive eye surgery."

Researchers from Mass Eye and Ear published a paper in the British Journal of Ophthalmology on "Contrast sensitivity function in patients with macular disease and good visual acuity" and conclude that "CSF measured with the qCSF active learning method was found to be significantly reduced in eyes affected by macular disease despite good VA compared with healthy control eyes."

Together with researchers from the Retina Foundation of the Southwest, we published a paper in the American Journal of Ophthalmology on "Normal and Low Luminance Automated Quantitative Contrast Sensitivity Assessment in Eyes with Age-Related Macular Degeneration". Results show that the CSF significantly differs between advancing stages of dry AMD, in particular when measured under low luminance conditions.

Joan W Miller, Mass Eye and Ear, will present her work on "Contrast Sensitivity Function in Non-Neovascular Age-related Macular Degeneration Measured with Active Learning" at The 44th Virtual Annual Macula Society Meeting, February 6-7, 2021. She concludes that "Early nnAMD was associated with reduced qCSF compared to controls as measured by novel active learning method, despite no difference in BCVA."

Together with researchers from Germany, France, and the US, we published a paper in Frontiers Neuroscience that shows the precision of the qCSF in people with Multiple Sclerosis.

US Naval Medical researchers investigated visual performance in pistol marksmen and with different military combat eye protection lenses. Paper accepted in Military Medicine.

We published a paper in Translational Vision Science and Technology, evaluating our qVA algorithm against ETDRS and FrACT. The paper was featured on the journal cover page!

Researchers from Mass Eye and Ear and the Kellog Eye Center published a paper in the Journal of VitreoRetinal Diseases on the qCSF in macula-off retinal detachment.

MEEI researchers showed that disorganisation of retinal inner layers is associated with reduced contrast sensitivity in retinal vein occlusion. Their study "highlights CS as an important functional endpoint for prospective clinical trials".

Researchers from AST, the Kellog Eye Center, and Mass Eye and Ear published a paper in Ophthalmic Surgery, Lasers and Imaging Retina on contrast sensitivity in retinal vein occlusion. The study finds that "CSF seems to be a promising visual function endpoint with potential applications in clinical practice and future clinical trials".

Researchers from Sun Yat-Sen University published a study in Eye.

Researchers from the University of Waterloo published an IOVS paper on contrast sensitivity in Para Nordic and Para Alpine skiers.

AST CEO Luis Andres Lesmes participated in a European Vision Institute special interest focus group on "New Technologies for Outcome Measures in Retina and Glaucoma". Click "View link" to read the report.

Researchers from the Wilmer Eye Institute publish a paper in IOVS.

In a collaboration with Ohio State University and New York University Shanghai, AST researchers have developed a new method for visual field mapping.

Researcher from the Southern California College of Optometry publishes a paper in Documenta Ophthalmologica.

John Miller, MD, Mass Eye and Ear Infirmary, will present results on "Active Learning of Contrast Sensitivity Deficits in Maculopathy with Good Acuity".

Click "View link" for more information

AST CEO Luis Lesmes will give an invited talk "Bayesian Adaptive Estimation of the Contrast Sensitivity Function" at a meeting of the European Vision Institute's Special Interest Focus Group "New Technologies for Outcome Measures in Retina and Glaucoma". The meeting will be hosted by the Institute of Molecular and Clinical Ophthalmology Basel on November 8th.

Click "View link" for more information

Researchers at the Kellog Eye Center of the University of Michigan evaluated OCT imaging, perimetry, e-ETDRS, and the quick CSF method for their effectiveness to diagnose and monitor early diabetic neuroretinal disease. They found that "Contrast sensitivity, as assessed by AULCSF and contrast sensitivity measurements at various spatial frequencies on the AST Platform, was the most sensitive test for detection of subtle functional differences in diabetic patients both with and without retinopathy". The paper is part of a special IOVS issue on "Biomarkers and Surrogate Endpoints in Ophthalmic Clinical Research".

US Navy researchers present their work on "Effects on Contrast Sensitivity Function following LASIK & PRK". They find that the "QCSF is a sensitive method in detecting functional visual changes during the recovery after refractive surgery"

John Miller, Mass Eye and Ear, presents his work on "A Novel Contrast Sensitivity Testing Device as a New Measure of Visual Recovery in Retinal Detachment". Click for a video interview.

Click "View link" for more information.

Die Wirtschaft (in German)

Researchers at the Joslin Diabetes Center, Boston, find that the quick CSF "may be a sensitive method to detect visual function changes resulting from diabetes and diabetic macular edema". Click "View link" for full abstract.

Click "View link" for more information

EyeWorld

Technologie-Blog Lübeck

Nature

Optometry Today

Salk Institute

Schepens Eye Research Institute